HollyBerry's toxic polycule

Guide

Note: the third treasure used on this is Jewelry Box and the preferred watch is the Sleepyhead Jelly watch but it not added yet lol.

Breakdown/Subs:

Hollyberry: This entire team is built around Hollyberry and makes use of her high def and damage absorb to let high-damage cookies go ham. Her toppings should aim to make her a wall to cover your team. Speed toppings are to maximize her buff on the team.

Pitaya Dragon: Pitaya's high damage and debuff makes for a punishing opening. They keep pressure on the other team as they chip away at the other's hp to cancel out any hp recovery.
Sub: Black Forest or any other high-offensive cookie that can chip away at hp will work.

Eternal Suger: Currently the best bomber in game, her mass debuffs and heavy bombing make sure a force of nature all her own.
Sub: White Lily or Moonlight is rec but any high aoe cookie works.

Black Pearl: Black Pearl ability to ignore the enemy team's defense and buff makes her deadly in pair with her ability which kneecaps hp recover. Her high damage makes her a shotgun that blasts massive chunks of hp off the other team.
Sub: Any Cookie that can skip past front line defense and deal pockets of high damage.

Mystic Flour: The best healer in game, her ability to nullify debuffs and quickly full heal the team with added hp shield synergies amazingly makes your team beefy and near impossible to kill eps if you choose to forgo an offense cookie for another tank on your front.
Sub: Pure Villina with a support cookie is your best bet to have a heal/buff combo on your team however this means removing either your aoe or ambush which isn't recommended. Pure or awaken Pure Villina works just fine if you're ok with only healing.
AN: I'm still new to the game and learning the meta any feedback is welcomed!

Tesaurses breakdown/subs:
Dream conductors whistle: It crit up buff Black pearl and Eternal Suger damage. it other buffs to atk and damage resist further stack your damage output.
Sub: Grim-looking Scythe boost it crit is a good sub if you can't pull the whistle.

Sleepyhead Jelly watch: An upgraded Jelly watch that adds an atk buff along with a cool-down decrease.
Sub: Jelly watch lol

Mysterious Jewelry Box: This box is a beast and with a high damage cookie it can near one-shot teams if their defense isn't good.
Sub: Echo of the Hurricane's Song is a good sub for it aoe damage.